A Study of LY4170156 in Participants With Selected Advanced Solid Tumors
Start Date
5/20/2024
Completion Date
4/1/2027
Summary
The purpose of this study is to find out whether the study drug, LY4170156, is safe, tolerable and effective in participants with advanced solid tumors. The study is conducted in two parts - phase Ia (dose-escalation, dose-optimization) and phase Ib (dose-expansion). The study will last up to approximately 4 years.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
LY4170156
bevacizumab
carboplatin
Itraconazole
pembrolizumab
Conditions
Locations
HonorHealth
Scottsdale, Arizona 85258
United States
University of California, San Diego (UCSD) - Moores Cancer Center
La Jolla, California 92037
United States
South Texas Accelerated Research Therapeutics (START) Midwest
Grand Rapids, Michigan 49546
United States
NYU Langone Health - Long Island
Mineola, New York 11501
United States
New York University (NYU) Clinical Cancer Center
New York, New York 10016
United States
David H. Koch Center for Cancer Care at Memorial Sloan Kettering Cancer Center
New York, New York 10065
United States
The Ohio State University (OSU) Wexner Medical Center
Columbus, Ohio 43210
United States
The University of Texas - MD Anderson Cancer Center
Houston, Texas 77030-4000
United States
START Mountain Region
West Valley City, Utah 84119
United States
Cancer Research SA
Adelaide, 5000
Australia
Icon Cancer Centre South Brisbane
QLD, 4101
Australia
Centre Leon Berard
Lyon, 69373
France
Institut de Cancerologie de l'Ouest - site St-Herblain
Saint-Herblain, 44805
France
Oncopole Claudius Regaud
Toulouse, 31059
France
Humanitas San Pio X
Milan, 20159
Italy
Istituto Europeo di Oncologia
Milan, 20141
Italy
Shizuoka Cancer Center
Shizuoka, 411-8777
Japan
National Cancer Center Hospital
Tokyo, 104-0045
Japan
Cancer Institute Hospital of JFCR
Tokyo, 135-8550
Japan
National Cancer Center
Goyang-si Gyeonggi-do, 10408
South Korea
Hospital Universitario Vall d'Hebron
Barcelona, 08035
Spain
Hospital Universitario 12 de Octubre
Madrid, 28041
Spain
Hospital Clinico Universitario de Valencia
Valencia, 46010
Spain