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NCT06445322Recruiting

Prescreening Study to Identify Potential Stargardt Participants for ACDN-01 Clinical Trials (STARPATH)

Ascidian Therapeutics, Inc

Start Date

6/20/2024

Completion Date

8/31/2030

Summary

This is an observational prescreening study. Individuals who are eligible for prescreening will undergo testing procedures that may be used to determine eligibility in ACDN-01 clinical trials.

Detailed Description

The prescreening process will be used to help determine the initial eligibility and interest of potential participants in ACDN-01 clinical trials by conducting assessments of key eligibility criteria before the clinical trial screening procedures are performed.

Eligibility Criteria

Age Range: 5 years to No maximum

Key Inclusion Criteria: * Presence of mutations in the ABCA4 gene * ABCA4 retinopathy phenotype (Stargardt disease type 1 or cone-rod dystrophy) Key Exclusion Criteria: * The presence of pathogenic or likely pathogenic mutations in other genes known to cause cone-rod dystrophy or Stargardt maculopathy * Retinal disease other than ABCA4-related retinopathy * Presence of a medical condition (systemic or ophthalmic), psychiatric condition, including substance abuse disorder, or physical examination or laboratory finding that may in the opinion of the principal investigator and sponsor preclude adherence to the scheduled study visits, safe participation in the study, or affect the results of the study.

Interventions

DIAGNOSTIC_TEST

Prescreening Assessments

Interested in This Trial?

Contact the trial locations directly using the information below to learn more about enrollment.

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Conditions

Stargardt DiseaseStargardt Disease 1Cone Rod DystrophyJuvenile Macular Degeneration

Locations

University of San Francisco

San Francisco, California 94158

United States

Vitreo Retinal Associates

Gainesville, Florida 32607

United States

Wilmer Eye Institute at John Hopkins

Baltimore, Maryland 21218

United States

Massachusetts Eye and Ear

Boston, Massachusetts 02114

United States

University of Michigan Kellogg Eye Center

Ann Arbor, Michigan 48105

United States

Cincinnati Eye Institute

Cincinnati, Ohio 45245

United States

Retina Foundation of Texas

Dallas, Texas 75382

United States

Retina Consultants of Texas

Houston, Texas 77401

United States