NCT06511232PHASE4Recruiting
Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction
The Methodist Hospital Research Institute
Start Date
8/19/2024
Completion Date
7/31/2029
Summary
The purpose of this study is to determine if intraosseous (IO) morphine decreases pain and post-operative opioid use in patients undergoing anterior cruciate ligament (ACL) reconstruction.
Eligibility Criteria
Age Range: 18 years to 40 years
Inclusion Criteria:
* Patients of the IRB approved surgeon(s) undergoing ACL reconstruction with bone-to-bone (BTB) autograft
* Patients aged between 18-40 years old at the time of surgery
Exclusion Criteria:
* Patients undergoing ACL reconstruction with any other type of autograft or allograft other than BTB
* Patients younger than 18 years old or older than 40 years old
* Patients undergoing meniscal root repair or any other repair that changes their weight-bearing status
* Patients with a history of substance abuse
* Vulnerable populations
* Patients on chronic pain medication within the last 6 months
* BMI \>/= 35
* Allergy to morphine
* Unwilling to participate
* Any additional reason the PI deems reasonable
Interventions
DRUG
Intraosseous Morphine
Conditions
Anterior Cruciate Ligament TearAnterior Cruciate Ligament InjuriesAnterior Cruciate Ligament Rupture
Locations
Houston Methodist Research Institute
Houston, Texas 77030
United States