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NCT06511232PHASE4Recruiting

Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction

The Methodist Hospital Research Institute

Start Date

8/19/2024

Completion Date

7/31/2029

Summary

The purpose of this study is to determine if intraosseous (IO) morphine decreases pain and post-operative opioid use in patients undergoing anterior cruciate ligament (ACL) reconstruction.

Eligibility Criteria

Age Range: 18 years to 40 years

Inclusion Criteria: * Patients of the IRB approved surgeon(s) undergoing ACL reconstruction with bone-to-bone (BTB) autograft * Patients aged between 18-40 years old at the time of surgery Exclusion Criteria: * Patients undergoing ACL reconstruction with any other type of autograft or allograft other than BTB * Patients younger than 18 years old or older than 40 years old * Patients undergoing meniscal root repair or any other repair that changes their weight-bearing status * Patients with a history of substance abuse * Vulnerable populations * Patients on chronic pain medication within the last 6 months * BMI \>/= 35 * Allergy to morphine * Unwilling to participate * Any additional reason the PI deems reasonable

Interventions

DRUG

Intraosseous Morphine

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Conditions

Anterior Cruciate Ligament TearAnterior Cruciate Ligament InjuriesAnterior Cruciate Ligament Rupture

Locations

Houston Methodist Research Institute

Houston, Texas 77030

United States