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NCT06593327NARecruiting

NT-ProBNP-based Heart Failure Screening and Prevention Trial in Patients With Type 2 Diabetes: STRONG-DM Study

University of Texas Southwestern Medical Center

Start Date

2/10/2025

Completion Date

12/15/2027

Summary

A pragmatic, randomized clinical trial to evaluate the effect of a heart failure (HF) risk assessment and prevention strategy incorporating HF clinical risk scores (WATCH-DM) with cardiac biomarker (NT-proBNP) paired with a clinical decision support tool to implement an intensive prevention strategy among patients with high risk focused on implementation of evidence-based HF preventive therapies.

Detailed Description

Primary care providers will be randomized to receive notifications via the electronic health record if any patients with diabetes have high heart failure risk based on a combination of clinical risk scores(WATCH-DM), and biomarkers (NT-proBNP). Providers will be provided recommendation to initiate evidence based therapies (SGLT2 inhibitors, GLP1 agonists, non-steroidal MRA) , obtain expert e-consultation, or refer the patient to a cardiometabolic risk management program.

Eligibility Criteria

Age Range: No minimum to No maximum

Inclusion Criteria: * Primary Care Provider that sees diabetes patients in clinic Exclusion Criteria: * Provider does not see patients with Diabetes

Interventions

BEHAVIORAL

Intensive Prevention Strategy

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Conditions

Type 2 DiabetesDiabetic CardiomyopathyHeart FailureCardiometabolic Diseases

Locations

University of Texas Southwestern Medical Center

Dallas, Texas 75209

United States