NCT06642610NARecruiting
CGM Dynamic Index for Predicting Prediabetes in Cystic Fibrosis
Indiana University
Start Date
6/15/2025
Completion Date
6/30/2026
Summary
The primary objective of this pilot study is to develop a CGM-based model to predict the progression from prediabetes to diabetes in individuals with cystic fibrosis.
Eligibility Criteria
Age Range: 12 years to 55 years
Inclusion Criteria:
* CF individuals aged 12-55 years.
* CF without diabetes or with prediabetes (as defined by OGTT and HbA1c).
* Willing to use a continuous glucose monitoring system with compatible smart phone for glucose data collection.
A person with CFRD and already using CGM, we will just collect their personal CGM data, and they are not required to have OGTT or HbA1c visit.
Exclusion Criteria:
* Pregnancy.
* History of transplant.
* Use of immunosuppressant drugs.
* Use of oral steroids or any medication known to interfere with glucose.
* Allergy to adhesives.
* Individuals with severe concurrent medical conditions that could confound glucose monitoring data (e.g., terminal illness, major organ failure).
* Conditions that may make unsafe for participants to do study or impair or confound the study at the discretion of the investigator
Interventions
DEVICE
CGM Dynamic Index (CDI)
Conditions
PrediabetesCystic Fibrosis (CF)Cystic Fibrosis-related Diabetes
Locations
Indiana University Health, University Hospital
Indianapolis, Indiana 46202
United States