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NCT06706752NARecruiting

A Study of Shengbai Oral Formula to Assess Safety and Alleviation of Adverse Effects in Cancer Patients Undergoing Chemotherapy

Sutter Health

Start Date

1/24/2025

Completion Date

12/1/2025

Summary

The goal of this clinical trial is to assess whether Shengbai Oral Formula is a viable option for treatment of fatigue, pain, and neutropenia in patients undergoing their third cycle of chemotherapy.

Eligibility Criteria

Age Range: 18 years to 80 years

Inclusion Criteria: 1. 18-80 years of age 2. A cancer diagnosis and scheduled to undergo at least three rounds of chemotherapy for curative or palliative intent 3. Chemotherapy is given at a minimum of every 2 weeks 4. At least 30 days past radiation therapy 5. Nonpregnant and use of method of contraception per the treating clinician standard of care 6. Life expectancy \> 3 months 7. Stable on all herbal or complementary therapeutics for the past 30 days and agree to not include new complementary therapeutics until after study completion 8. Baseline ECOG ≤ 2 9. In the opinion of the investigator, the subject will be compliant and have a high probability of completing the study including all scheduled evaluations and required tests Exclusion Criteria: 1. Abnormal ALT/AST: \> 2.5 to 3 times normal range 2. eGFR \<60 3. Platelets \< 75,000 4. Hb \<8.0 5. ANC \<1000 6. Documentation of a bone marrow transplant 7. Documentation of brain metastases, diagnosis with other cancer, except skin cancer history with basal cell carcinoma, squamous carcinoma 8. Documentation of current seizure disorder 9. Documentation of new cardiac arrhythmias and myocardial infarction 10. Any active bacterial or viral infection, pneumonia, sepsis, active gastric ulcer, gastritis, nonhealing wound, intractable nausea or vomiting, diarrhea, bleeding disorder 11. Hyperthyroidism, connective tissue disease including systemic lupus erythematous, rheumatoid arthritis 12. Documentation of a current drug abuse disorder 13. Current participation in other clinical trial

Interventions

DIETARY_SUPPLEMENT

Shengbai Oral Formula

OTHER

Inactive Placebo

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Conditions

Cancer

Locations

Sutter Health

Oakland, California 94609

United States