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NCT06819033PHASE4Recruiting

Effects of Photobiomodulation (PBM) on Pain After Presentation of Aphthous Ulcers in Pediatric Dental Patients

The University of Texas Health Science Center, Houston

Start Date

3/10/2025

Completion Date

2/28/2026

Summary

The purpose of this study is to compare the efficacy of laser photobiomodulation and "Magic Mouthwash" for treatment of pain in pediatric patients with aphthous ulcers , to assess how photobiomodulation influences the rate of healing of aphthous ulcers in pediatric patients and to measure changes in pain levels reported by pediatric patients undergoing photobiomodulation treatment for aphthous ulcers.

Eligibility Criteria

Age Range: 5 years to 17 years

Inclusion Criteria: * Patient/guardian speaks either English or Spanish * Patient presenting with one or more aphthous ulcers in their mouth, identified during a scheduled dental appointment * No previous PBM treatment to the presenting aphthous ulcer(s) * Guardian able to partake in a follow-up phone call in either the English or Spanish language Exclusion Criteria: * Patient presents with aphthous ulcers recently treated with PBM * Patient presents with herpes labialis (cold sores) * Patients presents with systemic disease that affects soft tissue/mucous healing

Interventions

DEVICE

PBM Therapy

DRUG

Maalox plus Benadryl

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Conditions

Aphthous Ulcer

Locations

The University of Texas Health Science Center at Houston

Houston, Texas 77030

United States