NCT06864715NARecruiting
Behavioral Activation for the PreVention of Post-strokE Depression in LoW-incomE Older Stroke Survivors
The University of Texas Health Science Center, Houston
Start Date
4/10/2026
Completion Date
11/1/2029
Summary
The overall objective of the project is to determine the effectiveness of tele-delivered behavioral activation (BA) by trained lay counselors (Tele-BA-S) to prevent Post-stroke depression (PSD) in low-income, older stroke survivors with subthreshold depression (SD).
Eligibility Criteria
Age Range: 55 years to No maximum
Inclusion Criteria:
* Enrollment within 3-months +2 weeks of a first-time ischemic or hemorrhagic stroke
* 24-item HDRS score \< 15 indicating subthreshold depression defined as the absence of depressive symptoms or presence of mild symptoms of depression
* Single person income less than or equal to $45,000
* Residing in a community residence
* Ability to speak and read in English or Spanish
* Mini-MoCA score \> or equal to 11
Exclusion Criteria:
* Stroke event unrelated to vascular risk factors (e.g., drug use) or transient ischemic attack
* 24-item HDRS score \> or equal to 15 indicating moderate to severe depression
* Actively participating in psychotherapy
* high suicide risk or severe psychiatric illness (e.g., bipolar disorder and active psychosis) and/or actively taking antipsychotics
* Diagnosed dementia and/or currently taking cognitive enhancers, amyloid-targeting medications, or orexin receptor antagonists
* Patient Health Questionnaire 9 score \> or equal to 10 and/or answers positive to Q9
* Diagnosed aphasia and/or severe cognitive impairments
* high-risk alcohol or drug misuse
* receiving medications for mood disorders and a change in dose or type within the last 4 weeks
Interventions
BEHAVIORAL
Tele-delivered Behavioral Activation by lay counselors after Stroke (Tele-BA-S)
BEHAVIORAL
Treatment as Usual
Conditions
Post-stroke DepressionSubthreshold Depression
Locations
The University of Texas Health Science Center at Houston
Houston, Texas 77030
United States