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NCT06906627NARecruiting

Implementation pRogram to Improve Screening and Management for CKD in Diabetes (Program 1) (IRIS-CKD)

Duke University

Start Date

10/28/2025

Completion Date

4/1/2027

Summary

IRIS-CKD is an implementation study to improve guideline-recommended screening of chronic kidney disease (CKD) in individuals with type 2 diabetes (T2D) in the United States.

Detailed Description

IRIS-CKD Screening Program: will focus on CKD screening in T2D. We will identify patients with T2D that have not received appropriate screening for CKD within the last 15 months and randomize patients to receive either a home kit to complete CKD screening ("home kit") versus a standard laboratory order ("laboratory order"). The primary objective is to evaluate whether delivery of home testing kits versus standard laboratory testing influences the degree to which patients receive guideline-recommended CKD screening. Patients will complete approximately 3 months of follow-up.

Eligibility Criteria

Age Range: 18 years to No maximum

Screening Program- Inclusion Criteria: * Adults with type 2 diabetes (T2D) * Receiving primary care within the healthcare system, Primary Care Provider (PCP) visit within the past 24 months (any PCP provider, including APP). * Lack of estimated glomerular filtration rate (eGFR) and/or urine albumin- creatinine ratio (UACR) measurement in the prior 15 months within the EHR Exclusion Criteria: • Chronic kidney disease (CKD) diagnosis

Interventions

OTHER

(IRIS-CKD Screening Program): Home Kit

OTHER

(IRIS-CKD Screening Program): Standard Lab Order

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Conditions

Chronic Kidney Disease(CKD)Type 2 DMType 2 Diabetes Mellitus (T2DM)

Locations

University of Alabama

Birmingham, Alabama 35233

United States

Orlando Health

St. Petersburg, Florida 33701

United States

University of Michigan

Ann Arbor, Michigan 48109

United States

Essentia Health

Duluth, Minnesota 55805

United States

Duke University

Durham, North Carolina 27707

United States

Houston Methodist

Houston, North Carolina 77030

United States

Baylor Scott & White

Temple, Texas 76508

United States