A Study to Learn About the Study Medicine Called Zavegepant (PF-07930207) in Children With a History of Migraine
Start Date
5/16/2025
Completion Date
8/12/2027
Summary
The purpose of the study is to learn about safety and how the body processes the study medicine called Zavegepant (PF-07930207) in children with a history of migraine. This study helps understand how the medicine is changed and removed from the body after taking it. This study is seeking participants who: * Are children aged between 6 and less than 12 years old * Have had migraine for at least 6 months. * Weigh more than 15 kilograms All participants in this study will receive zavegepant as a nasal spray once (one spray into one nostril). The dose of the study medicine that each participant receives will depend on how much the participant weighs. The study will look at the experiences of the participants receiving the study medicine and collect data to better understand the possible benefits and unwanted effects of different doses of the study medicine. Participants will take part in this study for up to 10 weeks. During this time, they will have 3 study visits at the study clinic, and 2 follow-up phone calls.
Eligibility Criteria
Age Range: 6 years to 11 years
Interventions
Zavegepant
Conditions
Locations
Arkansas Children's Hospital
Little Rock, Arkansas 72202
United States
Velocity Clinical Research, Washington DC
Washington D.C., District of Columbia 20016
United States
Coastal Heritage Clinical Research
Hinesville, Georgia 31313
United States
Clinical Research Institute
Minneapolis, Minnesota 55402
United States
Children's Hospital & Medical Center
Omaha, Nebraska 68114
United States
True North Neurology
Port Jefferson Station, New York 11776
United States
Accellacare - Piedmont
Statesville, North Carolina 28625
United States
Accellacare of Piedmont HealthCare
Statesville, North Carolina 28625
United States
Accellacare US Inc.
Winston-Salem, North Carolina 27103
United States
Central States Research
Tulsa, Oklahoma 74136
United States
Cedar Health Research
Dallas, Texas 75251
United States
Wasatch Clinical Research, LLC
Salt Lake City, Utah 84107
United States
Granger Medical Holladay - Holladay Clinic
Salt Lake City, Utah 84117
United States