NCT07109427NARecruitingAccepts Healthy Volunteers
Impact of an Electronic Health Record Maintenance Alert on PSA Screening Rates in a 10-Hospital Integrated Health System
Washington University School of Medicine
Start Date
8/11/2025
Completion Date
8/31/2031
Summary
\- The investigators propose a clinical trial to evaluate the impact of annual shared decision making for PSA screening, supported by system-level enhancements to promote evidence-based care: * Defined referral thresholds within the health maintenance reminder, aligned with clinical risk stratification per NCCN guidelines. * Enhanced clinical decision support (CDS) tools to reduce provider variation and ensure guideline-concordant screening and referral practices. * The goal is to reduce late-stage presentation without increasing overdiagnosis-ensuring that prostate cancer screening is both accessible and clinically effective.
Eligibility Criteria
Age Range: 40 years to 75 years
Eligibility Criteria:
* Receive care within the BJC Health System
* Have had at least one primary care physician appointment in the calendar year of PSA screening (primary care)
* Be male
* Not have a history of prostate cancer
* Meet one of the following risk criteria:
* High Risk for Prostate Cancer
* African American, between the ages of 40 and 75 (inclusive), or
* Family history of prostate, breast, ovarian, and/or pancreatic cancer, or
* Known familial germline mutation OR
* Average Risk for Prostate Cancer
* Between the ages of 50 and 75 (inclusive)
Interventions
OTHER
Annual PSA Health Maintenance Reminder
Conditions
Prostate CancerCancer of the Prostate
Locations
Washington University School of Medicine
St Louis, Missouri 63110
United States