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NCT07136688NARecruiting

Tibial Nerve Stimulation for Pediatric Spina Bifida Neurogenic Bladder

The University of Texas Health Science Center, Houston

Start Date

3/27/2026

Completion Date

8/11/2027

Summary

The purpose of this study is to determine the safety, feasibility, and compliance of a daily home transcutaneous tibial nerve stimulation (tTNS) protocol in children with chronic neurogenic bladder (NB) provided by self or caregiver for 4 weeks and to estimate the efficacy of tTNS

Eligibility Criteria

Age Range: 4 years to 17 years

Inclusion Criteria: * chronic neurogenic bladder * Spina Bifida diagnosis * Use of overactive bladder medication(s) * Stable bladder medications for ≥ 3 months Exclusion Criteria: * Progressive SCI (ex: transverse myelitis, polio, etc.) * Other lower urinary tract pathology or surgery * 2+ pitting edema in the legs that does not resolve * Known peripheral neuropathy or injury to the path of the tibial nerve * Cancer in the tibial nerve pathway and/or lower urinary tract * Inability to elicit the motor response with electric stimulation * Inability to complete the tTNS proficiency checklist (guardians) * Non-English speaking (guardians)

Interventions

DEVICE

Stamobil electric stimulator

DEVICE

sham tTNS device

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Conditions

Neurogenic Bladder Due to Spina Bifida

Locations

The University of Texas Health Science Center and Houston

Houston, Texas 77030

United States