NCT07140757Recruiting
Radiofrequency Ablation for Management of Benign/Indeterminate Thyroid Nodules and Low Risk Papillary Thyroid Cancers
M.D. Anderson Cancer Center
Start Date
8/18/2025
Completion Date
12/31/2030
Summary
To track the outcomes of patients who have been treated with RFA and its long-term effectiveness, and to learn more about the quality of life of patients who have received RFA in this study.
Detailed Description
Primary Objectives • To evaluate thyroid nodule volume changes over time in participants undergoing RFA as part of clinical care Secondary Objectives * To establish the health-related quality of life among participants undergoing with ultrasound guided RFA. * To evaluate the sonographic features of thyroid nodules over time following ultrasound guided RFA. * To assess adverse events rates following ultrasound guided RFA.
Eligibility Criteria
Age Range: 18 years to No maximum
Eligibility Criteria
1. Participants scheduled to undergo ultrasound-guided RFA for the following conditions: benign thyroid nodules, indeterminate thyroid nodules, low-risk DTC, and recurrent PTC
2. Participant is over 18 years and is either not a surgical candidate or has declined surgery.
3. Capable and willing to provide written informed consent
4. Participant has one of the following diagnoses:
* Biopsy-proven benign thyroid nodules causing compressive and/or cosmetic symptoms who are requesting treatment,
* Biopsy-proven indeterminate nodules (AUS or follicular neoplasm)
* Papillary thyroid carcinoma (PTC) without metastasis
* Locally recurrent thyroid cancer (\< 2 cm).
Exclusion Criteria
1. Participants meeting any of the following criteria will be excluded:
2. Participants considered unsuitable for RFA by the treating physician
Interventions
OTHER
Questionnaire
Conditions
Low RiskPapillary Thyroid CancerRadiofrequency Ablation
Locations
MD Anderson Cancer Center
Houston, Texas 77030
United States