Home-based Oral Glucose Tolerance Test for Type 1 Diabetes Screening
Start Date
8/26/2025
Completion Date
9/1/2027
Summary
This study aims at quantifying the accuracy of a self-administered fingerstick based glucose tolerance test (GTT@Home) respect to the gold-standard in-clinic venous plasma measures during the oral glucose tolerance test (OGTT) across a wide range of glycemic values in people at risk for clinical type 1 diabetes (T1D) (carriers of at least one islet autoantibody) or with new onset Stage 3 T1D within 100 days from the diagnosis.
Detailed Description
Investigators will conduct an observational longitudinal study that will include one home-based unsupervised GTT@Home test, a standard OGTT at a research facility and a supervised GTT@Home. Additionally, participants will have up to10-day blinded-CGM data collected.
Eligibility Criteria
Age Range: 8 years to 45 years
Interventions
GTT@Home
Conditions
Locations
Yale University Pediatric and Adult Diabetes Clinic
New Haven, Connecticut 06520
United States