Maximizing Laser Therapy Success for Port-Wine Birthmarks in Pediatric Patients
Start Date
7/1/2026
Completion Date
9/1/2028
Summary
In this study the investigators aim to optimize Port-Wine-Birthmark (PBW) laser therapy in children in order to reduce the number of laser treatments required for clearance and improve outcomes for refractory cases. This approach also seeks to reduce the frequency with which children require general anesthesia for treatment.
Detailed Description
Participants will undergo up to two laser treatment sessions on the Port-Wine Birthmark (PWB), in which five treatment modalities will be applied. The modality with the best outcomes will be used for subsequent treatments until the PWB is cleared or treatment with that modality reaches an outcome plateau, as determined by the treating physician. If no further outcome response is observed with that modality, the patient will undergo a second round of the five different modalities to determine if there are differences in efficacy. The treatment modality showing the best response will then be continued. Patient outcomes will then be analyzed to determine if there are significant differences between treatment modalities as well as among primary treatment patients and refractory cases.
Eligibility Criteria
Age Range: No minimum to 18 years
Interventions
Pulse Dye laser
Pulse Dye Laser (PDL) pulse width stacking
Pulse Dye Laser (PDL) followed by Nd:YAG (Neodymium-doped Yttrium Aluminum Garnet laser) laser.
IPL (Intense Pulsed Light) followed by Pulse Dye Laser (PDL)
Cupping followed by Pulse Dye Laser (PDL)
Conditions
Locations
Children's Medical Center
Dallas, Texas 75207
United States
Children's Medical Center
Plano, Texas 75024
United States