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NCT07218263Recruiting

AI Platform for Fatigue and Depression Detection

Brijesh Patel

Start Date

12/1/2025

Completion Date

5/1/2026

Summary

This observational study evaluates the accuracy of the Okaya AI platform in detecting fatigue and depression in cardiology patients, comparing its assessments to PHQ-9 and Fatigue Assessment Scale scores.

Detailed Description

Patients frequently experience fatigue and depression, which are often underdiagnosed due to limitations in traditional screening tools. This study introduces the Okaya platform, a browser-based AI system that analyzes facial and vocal biomarkers collected during conversational check-ins. The platform uses computer vision and natural language processing to extract features such as eye contact, facial affect, pitch, volume, and speech patterns. These features are processed through regression models to generate a composite AI based score. The study aims to validate this score against PHQ-9 and FAS assessments. Participants will complete a single baseline check-in using the Okaya platform and complete standard questionnaires. No interventions will be provided.

Eligibility Criteria

Age Range: 18 years to 99 years

Inclusion Criteria: * Age ≥18, English-speaking, able to consent Exclusion Criteria: * Active substance use, nonverbal, cognitive disability, active suicidal/homicidal ideation

Interventions

DIAGNOSTIC_TEST

Participants will complete PHQ-9, FAS, and Okaya assessments.

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Conditions

Depression DisordersFatigue SymptomCardiovascular

Locations

Indiana University

Indianapolis, Indiana 46074

United States

Methodist Hospital

Indianapolis, Indiana 46202

United States