A Multicenter Prospective Observational Cohort Study Evaluating the Impact of Cancer-Directed Treatment and Medication Use, Including Cannabis Use, in Multiple Myeloma Patients
Start Date
1/21/2026
Completion Date
8/22/2030
Summary
This study assesses the impact of cannabis (also commonly called marijuana, weed, or THC) use on quality of life among patients with multiple myeloma who are receiving chemotherapy. It also evaluates the potential benefits and harms of cannabis use.
Detailed Description
PRIMARY OBJECTIVES: I. Characterize and compare longitudinal patterns in quality of life, as assessed by the Functional Assessment of Cancer Therapy-Multiple Myeloma (FACT-MM) instrument, among cannabis users and non-users. II. Estimate and characterize the potential therapeutic benefit and adverse effects associated with cannabis use as assessed by longitudinal patterns of patient reported symptoms (Edmonton Symptoms Assessment Scale-ESAS) and medical assessments (Common Terminology Criteria for Adverse Events-CTCAE v5.0) through a comparative analysis of users and non-users. OUTLINE: This is an observational study. Participants are assigned to 1 of 2 groups. GROUP I: Patients complete surveys and undergo blood sample collection throughout the study. GROUP II: Healthcare providers complete a survey on study.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
Non-Interventional Study
Conditions
Locations
CTCA at Western Regional Medical Center
Goodyear, Arizona 85338
United States
City of Hope Medical Center
Duarte, California 91010
United States
City of Hope Seacliff
Huntington Beach, California 92648
United States
City of Hope at Irvine Lennar
Irvine, California 92618
United States
City of Hope at Long Beach Elm
Long Beach, California 90813
United States
City of Hope at Newport Beach Fashion Island
Newport Beach, California 92660
United States
City of Hope South Pasadena
South Pasadena, California 91030
United States
City of Hope Upland
Upland, California 91786
United States
City of Hope West Covina
West Covina, California 91790
United States
City of Hope Atlanta Cancer Center
Newnan, Georgia 30265
United States
City of Hope at Chicago
Zion, Illinois 60099
United States