Determine the Prevalence of Exocrine Pancreatic Insufficiency (EPI) in Pediatric and Adult Participants With Alagille Syndrome After Liver Transplantation
Start Date
8/3/2026
Completion Date
8/1/2028
Summary
The goal of this clinical trial is to determine the prevalence of exocrine pancreatic insufficiency (EPI) in a population of pediatric and adult participants with Alagille Syndrome (ALGS) post liver transplant. During the study, participants will: * Consume a high fat diet * Keep a diary of their abdominal signs and symptoms, and stool frequency and consistency * Collect stool for laboratory testing
Eligibility Criteria
Age Range: 7 years to 50 years
Interventions
Fecal Fat
Conditions
Locations
Children's Hospital Colorado - Research Institute
Aurora, Colorado 80045
United States
Hassenfeld Children's Hospital at NYU Langone
New York, New York 10016
United States
Cincinnati Children's Hospital Medical Center
Cincinnati, Ohio 45229
United States
Research Institute at Nationwide Children's Hospital
Columbus, Ohio 43205
United States
Oregon Health & Science University
Portland, Oregon 97239
United States
Vanderbilt University Medical Center
Nashville, Tennessee 37232
United States
Pediatric GI of El Paso
El Paso, Texas 79936
United States
Seattle Children's Hospital - Research Institute
Seattle, Washington 98105
United States