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NCT07337915NARecruiting

Improving Sleep In Midlife Women

The University of Texas Medical Branch, Galveston

Start Date

2/16/2026

Completion Date

8/31/2027

Summary

This study purpose of this study to see how consuming pistachios and completing a health intervention session a study therapist may improve sleep health in midlife women with poor sleep. Participants in this study will be asked to consume a study snack for about one month, complete a health education session with a study therapist and record information about their sleep. At baseline and after the intervention we will collect information about sleep, alertness, body composition, and blood lipids.

Eligibility Criteria

Age Range: 45 years to 65 years

Inclusion Criteria: * All races and ethnic backgrounds * Between the ages of 45-65 years old * Women who meet STRAW staging criteria for late peri-menopause (STRAW score of -1) defined as interval of amenorrhea of 60 days OR meet STRAW staging criteria for early post-menopause (STRAW score of +1a, +1b or +1c) defined as \>12 months since last menstrual period * History of poor sleep quality (Pittsburgh Sleep Quality Index score \> 5) * Able and willing to provide informed consent * Access to an electronic device with teleconferencing capabilities (Teams, etc) * Willing to consume study intervention * Fluent (able to read and write) in English Exclusion Criteria: * Pregnancy or lactation * Recent (within the last 3 months) or current use of any prescription or over the counter medications that may impact sleep quality: 1. including, systemic steroids, anabolic steroids, growth hormone, immunosuppressants, psychotherapy) 2. recent (within the last 3 months) change in antidepressant medication useage or dosage * Untreated comorbid sleep disorders that are no known to be responsive to the behavioral interventions: These sleep disorders include but are not limited to narcolepsy, circadian rhythm disorder/shift work, restless leg syndrome, periodic leg movement disorder, obstructive sleep apnea. * Evidence of recent severe mental health disorders (e.g., suicide attempt or psychiatric hospitalization in past 3 years) that would, in the opinion of the investigator, affect sleep and/or make it difficult for the participant to the investigators instructions. * Recent (within past 3 years) treated cancer other than basal cell carcinoma * Current adherence to a weight-loss or weight-gain diet or use of GLP-1 RA medications * Active or recent (within the past 12 months) alcohol or substance use disorder * Allergy to study intervention (tree nuts) * Any other condition or event considered exclusionary by study PI

Interventions

BEHAVIORAL

HealthyHabits1

BEHAVIORAL

HealthyHabits2

OTHER

Snack 2

OTHER

Snack 1

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Conditions

Poor Sleep Quality

Locations

University of Texas Medical Branch

Galveston, Texas 77555

United States