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NCT07419425PHASE4RecruitingAccepts Healthy Volunteers

My Path to Quit Tobacco

University of Wisconsin, Madison

Start Date

7/6/2026

Completion Date

1/1/2030

Summary

The overarching goal of this program of research is to reduce smoking-related health disparities by increasing smoking cessation among Black adults. The goal of this research proposal is to determine whether more intensive, culturally specific, evidence-based interventions are more effective at promoting long-term cessation and other key patient-centered outcomes compared to the usual evidence-based standard of care: services provided by a state-run quitline. This study compares the relative effectiveness of three different treatments (Standard, Intensive, and Intensive Incentivized) on long-term smoking cessation (biochemically confirmed abstinence from combusted tobacco at 26-weeks post-target quit day) among Black adults who smoke and want to quit.

Detailed Description

Primary Objective: Identify the most effective treatment for increasing long-term smoking abstinence among Black adults who smoke. Secondary Objectives: * Compare the 3 interventions on key patient-relevant outcomes (e.g., treatment satisfaction, smoke fewer cigarettes per day, quality of life) using validated measures collected at 8 and 26 weeks post-target quit day (TQD) * Identify subgroups for whom these treatments are especially effective or ineffective with respect to the primary and secondary outcomes. * Compare indices of treatment engagement (e.g., percentage of counseling sessions attended, percentage of days used nicotine patch) among Black people who smoke and are randomly assigned to the 3 different treatment conditions.

Eligibility Criteria

Age Range: 21 years to No maximum

Inclusion Criteria: * self-identify as Black * smoke cigarettes (greater than or equal to 1 cigarette on greater than or equal to 4 days/week) * motivated to quit smoking * willing to discontinue any non-study smoking cessation pharmacotherapy use during study treatment. Exclusion Criteria: * currently taking bupropion for non-smoking cessation reasons

Interventions

DRUG

Nicotine patch

OTHER

Quitline Counseling Phone Calls

OTHER

Counseling Sessions

OTHER

Pathways to Freedom

OTHER

Monetary Incentive

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Conditions

Smoking Cessation

Locations

Arizona State University

Phoenix, Arizona 85004

United States

Indiana University

Indianapolis, Indiana 46202

United States

University of Kansas Medical Center Research Institute, Inc

Kansas City, Kansas 66160

United States

Virginia Commonwealth University

Richmond, Virginia 23298

United States

UW School of Medicine and Public Health

Milwaukee, Wisconsin 53233

United States