Remote Ischemic Conditioning for PwSCI
Start Date
2/23/2026
Completion Date
7/30/2027
Summary
The long-term goal of this project is to improve the overall cardiometabolic health of persons with spinal cord injury (SCI). This pilot study will test the feasibility and acceptability of remote ischemic conditioning implemented in a home setting by persons with SCI and collect cardiometabolic health outcomes to inform appropriate outcomes for a future larger trial. Researchers will compare, RIC high dose using standard blood pressure cuff to RIC high dose using automated blood flow restriction cuff to RIC low dose using standard blood pressure cuff, to determine cardiometabolic health improvements amongst groups. Participants will: Complete an initial 2-day assessment, participate in a 6-week intervention using remote ischemic conditioning (RIC) within their home, complete a 2-day post assessment.
Detailed Description
The goal of this clinical trial is to collect preliminary data on examining the effects of remote ischemic conditioning (RIC) on cardiometabolic health outcomes for persons with spinal cord injury (SCI). The main aims are: To identify barriers, facilitators and reasons for positive determinants for implementation of RIC in a home setting. To estimate improvements in cardiometabolic health of participants with SCI enrolled in an in-home, high-dose RIC intervention group compared to a low-dose RIC group. The long-term impact will be implementing evidence-based interventions that are achievable and accessible to persons with SCI for improving cardiovascular and metabolic morbidity and mortality outcomes.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
RIC high-dose standard blood pressure cuff
RIC high-dose automated blood flow restriction cuff
RIC low-dose standard blood pressure cuff
Conditions
Locations
Washington University School of Medicine
St Louis, Missouri 63108
United States