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NCT06330181NARecruiting

Virtual Walking Therapy for Neuropathic Pain Following Incomplete Spinal Cord Injury

Texas A&M University

Start Date

12/2/2024

Completion Date

1/1/2027

Summary

The purpose of this study is to determine if playing a virtual reality walking game can help improve neuropathic pain in adults with incomplete spinal cord injury.

Detailed Description

Many people with SCI experience neuropathic pain. Neuropathic pain is often described as sharp, burning, or electric. 'Traditional' treatments often do not do a good job of reducing neuropathic pain. Therefore, it is important to see if 'non-traditional' treatments might work. Scientists think that neuropathic pain occurs in SCI because the sensations coming from the eyes and up the spinal cord to the brain do not match what the brain thinks it told the body to do. This 'mismatch' may result in changes in the brain that make neuropathic pain possible. Virtual reality walking may potentially reduce this 'mismatch' by creating the 'illusion' that the person is walking. The brain then thinks it is telling the body to walk AND the information coming from the eyes matches its instructions. This 'matching' may reverse the brain changes that make neuropathic pain possible. The current study is specifically focused on individuals whose SCI has been classified as incomplete (ASIA B, C, or D).

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: The study will recruit individuals with incomplete injury (American Spinal Injury Association \[ASIA\] classification B, C, or D) with lumbar, paraplegic, or low tetraplegic (C5-C7) injury. Additional criteria will include: 1. Must have persistent NP symptoms that are of daily severity of at least 4/10 for 3 or more months 2. Must endorse more than 2 items on a 7-item Spinal Cord Injury Pain Instrument, SCIPI 3. Must be 18 years of age or older 4. Must be more than one and a half years post-injury to begin study (can be screened at an earlier time for eligibility) 5. Must have mobile connectivity with usable service 6. Must be stable on pain medication for 1 or more months 7. Must be cleared on the VRWalk physical activity clearance scale 8. Must not have motion sickness that interferes with daily life 9. Must use a wheelchair at least 75% of the time Exclusion Criteria: 1. Individuals with Injury levels between C1 and C4 2. Individuals under the age of 18 3. Individuals who were injured within the past year 4. Individuals who cannot comprehend spoken English 5. Individuals who are in prison 6. Individuals who are blind 7. Individuals who experience severe motion sickness

Interventions

OTHER

VR Game 1

OTHER

VR Game 2

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Conditions

Spinal Cord InjuriesNeuropathic Pain

Locations

Texas A&M University

College Station, Texas 77843

United States