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NCT07556159Recruiting

A Study Evaluating Disease Characteristics and Outcomes in Participants With Asthma in Routine Clinical Practice

Sanofi

Start Date

4/1/2026

Completion Date

4/4/2029

Summary

The main aim of the study to describe the characteristics of participants with asthma across the spectrum of disease severity, including sociodemographic and clinical characteristics, treatment and disease burden, biomarkers, and both disease-specific and generic health-related quality of life. The study consists of two parts: a cross-sectional study, and a prospective follow-up evaluate changes in disease trajectories in participants with asthma.

Eligibility Criteria

Age Range: 6 years to No maximum

Inclusion Criteria: Applicable for Part 1 participants: * Age 6 years and older, at the time of signing the informed consent * Physician diagnosis of asthma for at least 12 months * Existing treatment with low, medium, or high dose ICS and other asthma therapies as reflected in GINA 2-5 steps * Participant or legally authorized representative (where applicable) has consented to participate Applicable for Part 2 participants: * Age 18 years and older, at the time of signing the informed consent. * Physician diagnosis of asthma for at least 12 months * Existing treatment with low or medium ICS and other asthma therapies as reflected in GINA 2-4 steps * Participant or legally authorized representative (where applicable) has consented to participate * Participants must meet the criteria for at least one of the cohorts below: A) Asthma control cohorts 1. ACQ-5 \>= 1.5 2. ACQ-5 \< 1.5 (B) Type-2 biomarker cohorts 3. Elevated T2 biomarkers (B1: Type-2-high cohort) 4. Low T2 biomarkers (B2: Type-2-low cohort) Participants are excluded from the study if any of the following criteria apply (applicable for both Part 1 and Part 2 participants): * Current diagnosis of chronic obstructive pulmonary disease (COPD) or congestive heart failure * Participants with moderate/severe cognitive impairment. * Participants with moderate/severe cardiac disease. * Participants on immunosuppressive medication for a chronic condition. * Participation in other interventional and noninterventional clinical study (currently or in the past 3 months) The above information is not intended to contain all considerations relevant to a participant's potential participation in a clinical trial.

Interventions

OTHER

Procedure: Investigational Procedures

OTHER

Procedure: Investigational Procedures

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Conditions

Asthma

Locations

Chandler Clinical Trials - Site Number: 840106

Chandler, Arizona 85224

United States

Del Sol Research Management, LLC - Mesa - Site Number: 840123

Mesa, Arizona 85206

United States

Sun City Clinical Trials - Elite - Site Number: 840120

Sun City, Arizona 85351

United States

FOMAT - Huntington Asthma & Allergy Center - Site Number: 840158

California City, California 91107

United States

Imax Clinical Trials - Site Number: 840109

La Palma, California 90623

United States

Newport Native MD, Inc. - Site Number: 840101

Newport Beach, California 92663

United States

Pasadena Clinical Trials - Site Number: 840116

Pasadena, California 91101

United States

Valiance Clinical Research (JPJ Research) - Site Number: 840135

Tarzana, California 91356

United States

Clinical Research of California - Site Number: 840145

Walnut Creek, California 94598

United States

Cornerstone Research Institute, LLC - Site Number: 840152

Altamonte Springs, Florida 32701

United States

3SYNC Research - Boca Raton - Site Number: 840148

Boca Raton, Florida 33431

United States

Meris Clinical Research - Site Number: 840167

Brandon, Florida 33511

United States

Finlay Medical Research - Site Number: 840107

Greenacres City, Florida 33467

United States

EMDA Clinical Research - Site Number: 840113

Miami, Florida 33126

United States

Finlay Medical Research - Miami - Site Number: 840110

Miami, Florida 33126

United States

Care Research Inc. - Site Number: 840103

Miami, Florida 33130

United States

L&A Morales Healthcare, Inc - Site Number: 840102

Miami, Florida 33142

United States

D&H National Research Centers INC - Site Number: 840128

Miami, Florida 33155

United States

Research Institute Of South Florida - Site Number: 840149

Miami, Florida 33173

United States

Valencia Medical & Research Center, Corp - Site Number: 840153

Miami, Florida 33174

United States

Correa Research Center, Inc. - Site Number: 840141

Miami, Florida 33186

United States

3SYNC Research - Miami Lakes - Site Number: 840146

Miami Lakes, Florida 33014

United States

Deluxe Health Center - Site Number: 840117

Miami Lakes, Florida 33014

United States

MedQuest Translation Sciences, LLC - Site Number: 840162

Miami Lakes, Florida 33016

United States

Biscayne Clinical Research - Site Number: 840157

North Miami Beach, Florida 33169

United States

Edward Jenner Research Group, LLC - Site Number: 840169

Plantation, Florida 33317

United States

Mark J. Pamer D.O., LLC - Site Number: 840121

Port Saint Lucie, Florida 34986

United States

Avita Clinical Research - Tampa - Site Number: 840125

Tampa, Florida 33613

United States

Palm Beach Medical & Research Center, Inc. - Site Number: 840165

West Palm Beach, Florida 33409

United States

The Allergy Center at Brookstone - Site Number: 840114

Columbus, Georgia 31904

United States

Next Innovation Clinical Research - Chicago - Site Number: 840159

Chicago, Illinois 60616

United States

Bluegrass Allergy Care - Lexington - Site Number:840112

Lexington, Kentucky 40509

United States

Velocity Clinical Research - Rockville - Site Number: 840163

Rockville, Maryland 20854

United States

Montana Medical Research - Site Number: 840137

Missoula, Montana 59808

United States

Primary Clinical Research, LLC - Papillion - Site Number: 840168

Papillion, Nebraska 68046

United States

MedCorps Asthma and Pulmonary Specialists LLC - Sewell - Site Number: 840136

Sewell, New Jersey 08080

United States

Finger Lakes Medical Research, PLLC - Site Number: 840155

Cortland, New York 13045

United States

Mid Hudson Medical Research, PLLC - Site Number: 840139

New Windsor, New York 12553

United States

Allergy Partners of Western North Carolina - Site Number: 840131

Asheville, North Carolina 28801

United States

NexGen Research - Site Number: 840154

Lima, Ohio 45801

United States

Toledo Institute of Clinical Research Inc - Site Number: 840105

Toledo, Ohio 43617

United States

Allergy and Clinical Immunology Associates - Site Number: 840127

Pittsburgh, Pennsylvania 15241

United States

Clinical Research of Rock Hill - Site Number: 840115

Rock Hill, South Carolina 29732

United States

Allergy Associates, PA dba Allergy, Asthma and Sinus Center - Site Number: 840144

Tennessee City, Tennessee 30909

United States

Southwest Family Medicine Associates - Site Number: 840126

Dallas, Texas 75235

United States

El Paso Pulmonary Association (EPPA) - West El Paso - Site Number: 840108

El Paso, Texas 79902

United States

Lumi Research - Site Number: 840156

Houston, Texas 77090

United States

Pioneer Research Solutions - Site Number: 840104

Houston, Texas 77099

United States

Lumi Research - Hurst - Site Number: 840164

Hurst, Texas 76054

United States

DM Clinical - Tomball - Site Number: 840130

Tomball, Texas 77081

United States

Bellingham Asthma, Allergy & Immunology Clinic - Site Number: 840138

Bellingham, Washington 98225

United States

Investigational Site Number: 124203

Calgary, Alberta T3R 1W7

Canada

Investigational Site Number: 124201

Windsor, Ontario N8X 2G1

Canada

Investigational Site Number: 392702

Takamatsu, Kagawa-ken 761-8073

Japan