A Study to Learn About the Study Medicine Called Berobenatide (PF-08653944) in People With Overweight or Obesity
Start Date
6/10/2026
Completion Date
6/21/2028
Summary
The purpose of this clinical study is to learn about the effects and safety of berobenatide (PF-08653944). This may help people with overweight or obesity lose weight. People in this study may also have type 2 diabetes. About 950 adults will be in this study. Berobenatide will be compared to a placebo. A placebo does not have any medicine in it but looks just like the medicine being studied. Berobenatide or placebo is given by a shot under the skin in the belly area. The objective of the study is to compare the experiences of people receiving berobenatide to those of the people who do not to assess if the study medicine is effective and safe. People will take part in this study for about 20 months. During this time, they will have about 15 study visits at the site. They will also have 2 study visits over the phone.
Eligibility Criteria
Age Range: 18 years to No maximum
Interventions
PF-08653944
Placebo
Conditions
Locations
ImmuniMet, LLC
Modesto, California 95350
United States
ClearVue Eye Care
Roseville, California 95661
United States
Clinical Trials Research
Sacramento, California 95821
United States
University Clinical Investigators, Inc.
Tustin, California 92780
United States
Diablo Clinical Research, Inc.
Walnut Creek, California 94598
United States
Nature Coast Clinical Research
Crystal River, Florida 34429
United States
West Coast Eye Institute
Lecanto, Florida 34461
United States
South Broward Research
Miramar, Florida 33027
United States
Suncoast Clinical Research, Inc.
New Port Richey, Florida 34652
United States
West Coast Medical Associates
New Port Richey, Florida 34652
United States
MediSphere Medical Research Center, LLC
Evansville, Indiana 47714
United States
Monroe Biomedical Research
Louisville, Kentucky 40213
United States
Aa Mrc Llc
Flint, Michigan 48504
United States
Albuquerque Clinical Trials, Inc.
Albuquerque, New Mexico 87102
United States
Rochester Clinical Research, LLC
Rochester, New York 14609
United States
Medication Management LLC
Greensboro, North Carolina 27405
United States
Midwest Eye Center
Cincinnati, Ohio 45202
United States
Velocity Clinical Research, Mt. Auburn
Cincinnati, Ohio 45219
United States
VIP Trials
San Antonio, Texas 78230
United States
York Clinical Research, LLC
Norfolk, Virginia 23504
United States
Medical Corporation Heishinkai OCROM Clinic
Suita, Osaka 565-0853
Japan
Tokyo Center Clinic
Chuo-ku, Tokyo 103-0027
Japan
Tokyo-Eki Center-Building Clinic
Chuo-ku, Tokyo 103-0027
Japan
Fukuwa Clinic
Chuo-ku, Tokyo 104-0031
Japan
Medical Corporation Heishinkai ToCROM Clinic
Shinjuku-ku, Tokyo 160-0008
Japan