NCT07599761PHASE1RecruitingAccepts Healthy Volunteers
A Phase 1 Study to Assess the Effect of Itraconazole on ABBV-722 in Healthy Adult Participants
AbbVie
Start Date
5/5/2026
Completion Date
7/1/2026
Summary
The objective of this study is to assess the effect of repeated doses of itraconazole on the single dose pharmacokinetics (PK) of ABBV-722.
Eligibility Criteria
Age Range: 18 years to 65 years
Inclusion Criteria:
* Laboratory values meet the criteria specified in the protocol.
* A condition of general good health, based upon the results of a medical history, physical examination, vital signs, laboratory profile, and a 12-lead electrocardiogram (ECG).
Exclusion Criteria:
* History of any clinically significant illness/infection/major febrile illness, hospitalization, or any surgical procedure within 30 days prior to the first dose of study treatment.
* Consumption of alcohol, grapefruit products, Seville oranges, starfruit products or quinine/tonic water within the 72-hour period prior to study treatment administration.
* Use of tobacco- or nicotine-containing products within 3 months (90 days) prior to the first dose of study treatment.
* Participant has prior exposure to ABBV-722 within 90 days prior to the first dose of study treatment.
Interventions
DRUG
ABBV-722
DRUG
Itraconazole
Conditions
Healthy Volunteers
Locations
Acpru /Id# 282143
Grayslake, Illinois 60030
United States