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NCT07616128PHASE2Recruiting

Study of EVO756 in Adults With Migraine

Evommune, Inc.

Start Date

6/1/2026

Completion Date

11/1/2027

Summary

This study will evaluate the efficacy and safety of EVO756 against placebo in adults with migraine.

Eligibility Criteria

Age Range: 18 years to 64 years

Key Inclusion Criteria: * Adults aged 18 to \<65 years * Migraine with or without aura, per ICHD-3 criteria * History of failure with prior preventive migraine treatments * Not currently using migraine preventive therapy Key Exclusion Criteria: * Difficulty distinguishing migraine from other headache types or presence of other primary headache disorders * Use of certain medications * Any clinically significant medical, psychiatric, neurological, cardiovascular, or laboratory abnormalities

Interventions

DRUG

EVO756, Dose 1

DRUG

EVO756, Dose 2

DRUG

Placebo

Interested in This Trial?

Contact the trial locations directly using the information below to learn more about enrollment.

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Conditions

Migraine

Locations

CA Medical Clinic for Headache

Los Angeles, California 90067

United States

New England Institute for Neurology and Headache

Stamford, Connecticut 06905

United States

Clinical Neuroscience Solutions, Inc.

Jacksonville, Florida 32256

United States

Apple Medical Research Group, Inc

Miami, Florida 331216

United States

Clinical Neuroscience Solutions, Inc.

Orlando, Florida 32819

United States

Vantage Clinical Trials

Tampa, Florida 33614

United States

Accel Research Site-Decatur-Alcanza

Decatur, Georgia 30030

United States

Michigan Headache and Neurological Institute

Ann Arbor, Michigan 48104

United States

Clinosis - Dent Neurologic Instite

Amherst, New York 14226

United States

Eximia Research NC

Raleigh, North Carolina 27607

United States

Clinical Trials of South Carolina

Charleston, South Carolina 29406

United States

FutureSearch Trials of Neurology

Austin, Texas 78731

United States

FutureSearch Trials of Dallas

Dallas, Texas 75251

United States

Vaught Neurological Services

Crab Orchard, West Virginia 25827

United States