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NCT07623668PHASE3Recruiting

Privosegtor Investigation in Optic Neuropathies Efficacy Evaluation Research

Oculis

Start Date

5/28/2026

Completion Date

12/1/2028

Summary

The goal of this clinical trial is to evaluate the safety and efficacy of privosegtor, a neuroprotective candidate, in patients diagnosed with optic neuritis (ON). Researchers will compare privosegtor and the standard of care (methylprednisolone) to a placebo and standard of care (methylprednisolone).

Eligibility Criteria

Age Range: 18 years to 50 years

Key Inclusion Criteria: * Adult men and women (aged 18 to 50 years) with the first episode of ON in the study eye, associated with unilateral visual loss. * Onset of visual loss symptoms in the previous 12 days before first administration of study treatment. Key Exclusion Criteria: \- Have a history or presence of any disorder or condition that may, in the opinion of the Investigator, likely interfere with the interpretation of the study results or participant safety

Interventions

DRUG

Privosegtor

DRUG

Methylprednisolone

OTHER

Placebo

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Conditions

Optic Neuritis

Locations

Kahana Oculoplastic and Orbital Surgery

Livonia, Michigan 48152

United States

Neuro-Eye Clinical Trials

Houston, Texas 77074

United States