NCT07631286NARecruitingAccepts Healthy Volunteers

Ejaculatory-Sparing HoLEP vs Standard HoLEP

Northwestern University

Start Date

6/1/2026

Completion Date

5/1/2028

Summary

The objective of this study is to compare a new surgical technique for HoLEP that will allow for sparing of ejaculation post-HoLEP.

Detailed Description

The primary aim of this study is to assess the efficacy of ejaculatory-sparing HoLEP (ES-HoLEP) in preserving ejaculation while also maintaining good urinary outcomes.

Eligibility Criteria

Age Range: 18 years to 100 years

Inclusion Criteria: \- Patients who are sexually active with antegrade ejaculation who are undergoing HoLEP for the treatment of bothersome lower urinary tract symptoms. Exclusion Criteria: * Patients with pre-existing retrograde ejaculation * Patients who are not sexually active * Patients with indwelling urinary catheter prior to surgery, neurological disease, or history of prior prostatic/urethral surgery that may impact ejaculation * Patients who lack decisional capacity * Patients unable to read/speak English

Interventions

OTHER

Ejaculatory-sparing (ES-sparing) HoLEP

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Conditions

Enlarged Prostate (BPH)Enlarged Prostate With Lower Urinary Tract Symptoms

Locations

Northwestern University

Chicago, Illinois 60611

United States