NCT07632742NARecruitingAccepts Healthy Volunteers

Moses 2.0 vs Magneto for HoLEP - a Randomized Controlled Trial

Northwestern University

Start Date

6/1/2026

Completion Date

6/1/2028

Summary

The objective of this study is to compare the Magneto 150 holmium laser to the current MOSES 2.0 technology to see if there is a benefit in decreased hemostasis time intraoperatively.

Detailed Description

The Magneto 150 is a high-powered 150W holmium laser that offers similar pulse-modulation benefits of MOSES 2.0, which facilitates effective dissection and enucleation of the tissue plane while also offering a new first-of-its kind proprietary Magneto setting which allows for very low peak power of 500W and longer pulse duration which allows for better hemostasis.

Eligibility Criteria

Age Range: 18 years to 100 years

Inclusion Criteria: * Undergoing HoLEP for the treatment of bothersome lower urinary tract symptoms * Internet access and a device to complete postoperative questionnaires (smartphone, tablet, laptop or desktop computer) Exclusion Criteria: * Patients who lack decisional capacity * Patients unable to read/speak English * Patients who are on a blood thinner (anticoagulation medication) * Patients who do not have internet access to complete postoperative surveys

Interventions

DEVICE

Magneto 150 holmium laser

DEVICE

Moses 2.0 holmium laser

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Conditions

Enlarged Prostate (BPH)Benign Prostatic Hyperplasia

Locations

Northwestern University

Chicago, Illinois 60611

United States