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NCT07676565Recruiting

Safety and Efficacy of Adjunct Therapies in Adults With Type 1 Diabetes: Multicenter, Registry Study

Indiana University

Start Date

3/24/2026

Completion Date

4/1/2028

Summary

This will be a multicenter registry-based study to evaluate safety and efficacy of GLP-1RA and SGLTi therapies in adjunct to insulin in adults with type 1 diabetes (T1D) over 1 year. This study will enroll participants who have been prescribed adjunct therapy as part of usual care.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: * Adults ≥18 years of age * Clinical diagnosis of T1D * GLP-1RA or SGLTi (SGLT-1 and SGLT-2 inhibitors) drug prescribed by their provider for any indication as part of usual care with use for no more than 1 week * Use of CGM and availability of CGM data for 1 month prior to enrollment and expected to be available throughout the study * Willing and able to provide informed consent Exclusion Criteria: * No exclusion criteria other than those not meeting inclusion criteria above

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Conditions

Type 1 Diabetes

Locations

Hoag Memorial Hospital

Newport Beach, California 92663

United States

Emory University

Atlanta, Georgia 30303

United States

Northwestern University

Chicago, Illinois 60611

United States

Maine Health Research Institute

Portland, Maine 04102

United States

Harvard Medical School

Boston, Massachusetts 02115

United States

Henry Ford Hospital

Detroit, Michigan 48202

United States

Mount Sinai

New York, New York 10029

United States