NCT07676565Recruiting
Safety and Efficacy of Adjunct Therapies in Adults With Type 1 Diabetes: Multicenter, Registry Study
Indiana University
Start Date
3/24/2026
Completion Date
4/1/2028
Summary
This will be a multicenter registry-based study to evaluate safety and efficacy of GLP-1RA and SGLTi therapies in adjunct to insulin in adults with type 1 diabetes (T1D) over 1 year. This study will enroll participants who have been prescribed adjunct therapy as part of usual care.
Eligibility Criteria
Age Range: 18 years to No maximum
Inclusion Criteria:
* Adults ≥18 years of age
* Clinical diagnosis of T1D
* GLP-1RA or SGLTi (SGLT-1 and SGLT-2 inhibitors) drug prescribed by their provider for any indication as part of usual care with use for no more than 1 week
* Use of CGM and availability of CGM data for 1 month prior to enrollment and expected to be available throughout the study
* Willing and able to provide informed consent
Exclusion Criteria:
* No exclusion criteria other than those not meeting inclusion criteria above
Conditions
Type 1 Diabetes
Locations
Hoag Memorial Hospital
Newport Beach, California 92663
United States
Emory University
Atlanta, Georgia 30303
United States
Northwestern University
Chicago, Illinois 60611
United States
Maine Health Research Institute
Portland, Maine 04102
United States
Harvard Medical School
Boston, Massachusetts 02115
United States
Henry Ford Hospital
Detroit, Michigan 48202
United States
Mount Sinai
New York, New York 10029
United States