American Lung Association (ALA) Lung Health Cohort
Start Date
10/29/2021
Completion Date
9/1/2026
Summary
The ALA-LHC is a longitudinal, multi-center cohort study that will enroll approximately 4,000 young adults between the ages of 25-35 who do not have severe lung disease. The overarching objective of the ALA-LHC is to establish a national cohort of young adults for the purpose of defining lung health and developing targets to intercept chronic lung disease at its earliest stages.
Detailed Description
The scientific goal of the study is to establish the relationship between a variety of factors (lifetime environmental exposures, fitness and physical activity, biomarkers, nasal respiratory epithelial transcriptome) and ideal versus impaired peak lung health (reserve and markers of susceptibility in investigators' model) in young adulthood. In addition to the initial baseline assessment, remote contacts (e.g., via text message, email, mail, or phone) at regular intervals will allow for both the retention of the participants as well as the collection of additional short-term follow-up information, i.e., within 4.5 years of enrollment. If additional funding becomes available, investigators will extend the study for an additional period of time to study factors related to long-term changes in lung health over time, i.e., at 5 years and beyond. Recruitment of participants will be conducted by the participating study sites along with national and regional efforts from the American Lung Association. Recruitment efforts will be supported by the study web site www.lung.org/lung-study
Eligibility Criteria
Age Range: 25 years to 35 years
Conditions
Locations
University Of Alabama
Birmingham, Alabama 35294
United States
University of Arizona-Tuscon
Tucson, Arizona 85724
United States
University of California, Los Angeles
Los Angeles, California 90095
United States
University of California, San Francisco
San Francisco, California 94143
United States
University of Colorado
Aurora, Colorado 80045
United States
National Jewish Health
Denver, Colorado 80206
United States
Nemours Children's Jacksonville
Jacksonville, Florida 32207
United States
University of Florida, Jacksonville
Jacksonville, Florida 32209
United States
University of Illinois at Chicago
Chicago, Illinois 60608
United States
Northwestern University
Chicago, Illinois 60611
United States
Rush Universtiy
Chicago, Illinois 60612
United States
University of Chicago
Chicago, Illinois 60637
United States
St. Vincent's Health System
Indianapolis, Indiana 46260
United States
University of Iowa
Iowa City, Iowa 52242
United States
University of Kansas
Kansas City, Kansas 66103
United States
Johns Hopkins University
Baltimore, Maryland 21218
United States
Brigham and Women's
Boston, Massachusetts 02115
United States
University of Michigan
Ann Arbor, Michigan 48109
United States
Presbyterian Brooklyn Methodist Hospital
Brooklyn, New York 11215
United States
New York Medical College
Hawthorne, New York 10532
United States
New York University
New York, New York 10016
United States
Mt. Sinai, NYC
New York, New York 10029
United States
Columbia University
New York, New York 10032
United States
Cornell University
New York, New York 10032
United States
University of Rochester
Rochester, New York 14642
United States
University of North Carolina Hospital
Chapel Hill, North Carolina 27517
United States
Duke University
Durham, North Carolina 27710
United States
Wake Forest School of Medicine
Winston-Salem, North Carolina 27104
United States
Ohio State University
Columbus, Ohio 43210
United States
Temple University
Philadelphia, Pennsylvania 19140
United States
University of Pittsburg-Emphysema/COPD Research Center
Pittsburgh, Pennsylvania 15213
United States
Medical University of South Carolina
Charleston, South Carolina 29425
United States
Vanderbilt University Medical Center
Nashville, Tennessee 37235
United States
Baylor College of Medicine
Houston, Texas 77030
United States
University of Vermont
Colchester, Vermont 05446
United States
University of Washington
Seattle, Washington 98108
United States
University of Wisconsin Madison
Madison, Wisconsin 53792
United States