NCT04750551NARecruiting
BreEStim for Post-Stroke Motor Recovery
The University of Texas Health Science Center, Houston
Start Date
11/1/2025
Completion Date
12/31/2027
Summary
The overall goal is to investigate the effectiveness of a novel intervention - Breathing-controlled electrical stimulation (BreEStim) on finger flexor spasticity reduction and hand function improvement in chronic stroke with moderate impairment.
Eligibility Criteria
Age Range: 18 years to 75 years
Inclusion criteria:
* has post stroke ≥ 6 months , medically stable;
* Unilateral, single stroke (no restriction on type (ischemic or hemorrhagic) or volume (large or small) of stroke);
* MAS score ≥ 1, i.e., detectable finger flexor hypertonia;
Exclusion criteria include:
* Patients with visual deficit/neglect; hearing or cognitive impairment;
* Patients with history of pulmonary disease (Asthma, chronic obstruction pulmonary disease, COPD);
* Patients that are currently adjusting tone alternating medications (e.g., baclofen), or
* Patients received botulinum toxin injection to the arm/fingers \<4 months, or phenol injections \< 2 years;
* Patients with a pacemaker;
* Women who are pregnant.
Interventions
DEVICE
BreEStim
DEVICE
EStim
Conditions
Motor Recovery
Locations
The University of Texas Health Science Center
Houston, Texas 77030
United States