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NCT04750564NARecruiting

BreEStim for Motor Recovery in Chronic Stroke With Severe Impairment (Pilot)

The University of Texas Health Science Center, Houston

Start Date

9/1/2025

Completion Date

12/31/2027

Summary

The overall goal is to investigate the effectiveness of a novel intervention - Breathing-controlled electrical stimulation (BreEStim) on finger flexor spasticity reduction and hand function improvement in chronic stroke with severe impairment.

Eligibility Criteria

Age Range: 18 years to 75 years

Inclusion criteria: * has post stroke ≥ 6 months , medically stable; * Unilateral, single stroke (no restriction on type (ischemic or hemorrhagic) or volume (large or small) of stroke); * MAS score ≥ 1, i.e., detectable finger flexor hypertonia; Exclusion criteria include: * Patients with visual deficit/neglect; hearing or cognitive impairment; * Patients with history of pulmonary disease (Asthma, chronic obstruction pulmonary disease, COPD); * Patients that are currently adjusting tone alternating medications (e.g., baclofen), or * Patients received botulinum toxin injection to the arm/fingers \<4 months, or phenol injections \< 2 years; * Patients with a pacemaker; * Women who are pregnant.

Interventions

DEVICE

BreEStim

DEVICE

EStim

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Conditions

Motor Recovery

Locations

The University of Texas Health Science Center

Houston, Texas 77030

United States