Does Nerve Block + Oral Dexamethasone Reduce Recurrence of Headache Within 72 Hrs?
Start Date
9/15/2023
Completion Date
1/30/2028
Summary
For some patients who come to the emergency department for treatment of a migraine headache, peripheral headache nerve blocks (PHNB) have proven to be an efficient and effective treatment for headache relief. Previous studies have demonstrated that adding steroids as an adjunct treatment to standard migraine treatment can reduce recurrence of headaches in the subsequent few days.
Detailed Description
Previous studies have provided evidence that administering steroids in addition to standard migraine headache treatment in the emergency department may reduce the recurrence of the headache within 24-72 hours. The standard migraine treatments in previous studies have been varied and include 5-HT receptor agonists, dopamine antagonists, dihydroergotamine, NSAIDS, and opioid analgesics. The steroids added to the standard treatment have been prednisone and dexamethasone (both IV and oral). This is the first study to examine the combination of peripheral nerve block as the primary treatment of migraine followed by oral dexamethasone to prevent recurrence.
Eligibility Criteria
Age Range: 18 years to 85 years
Interventions
Dexamethasone Oral
Placebo
Conditions
Locations
University Medical Center of El Paso
El Paso, Texas 79905
United States