NCT06071377RecruitingAccepts Healthy Volunteers
Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)
National Alliance for Sickle Cell Centers
Start Date
4/1/2023
Completion Date
2/1/2027
Summary
The main purpose of this study is to create a longitudinal cohort of those with Sickle Cell Trait (SCT) to better understand the hematologic phenotype for those that carry HbS, assess for differences in those with varying quantities of HbS and assess for potential clinical complications of SCT.
Eligibility Criteria
Age Range: 18 years to No maximum
Inclusion Criteria:
1. Are willing to voluntarily participate and sign the study consent
2. Know/suspect they have SCT and are willing to get tested to confirm/learn about their SCT status
3. Adults ages 18 and older
Exclusion Criteria:
1. Unwilling to sign consent
2. Known end-stage renal disease or dialysis
3. Known SCD (including sickle cell-beta thalassemia)
4. People who do not have SCT
Interventions
OTHER
Biologic Specimen Collection
Conditions
Sickle Cell Trait
Locations
University of Alabama
Birmingham, Alabama 35294
United States
Nemours Children's Hospital
Wilmington, Delaware 19803
United States
Indiana University
Indianapolis, Indiana 46202
United States
Functional Fluidics
Detroit, Michigan 48202
United States
University of North Carolina
Chapel Hill, North Carolina 27599
United States
Duke University
Durham, North Carolina 27710
United States
East Carolina University
Greenville, North Carolina 27834
United States
UT Health Houston
Houston, Texas 77030
United States