NCT06071377RecruitingAccepts Healthy Volunteers

Achieving Understanding of the Natural History of Sickle Cell Trait (AUNT)

National Alliance for Sickle Cell Centers

Start Date

4/1/2023

Completion Date

2/1/2027

Summary

The main purpose of this study is to create a longitudinal cohort of those with Sickle Cell Trait (SCT) to better understand the hematologic phenotype for those that carry HbS, assess for differences in those with varying quantities of HbS and assess for potential clinical complications of SCT.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: 1. Are willing to voluntarily participate and sign the study consent 2. Know/suspect they have SCT and are willing to get tested to confirm/learn about their SCT status 3. Adults ages 18 and older Exclusion Criteria: 1. Unwilling to sign consent 2. Known end-stage renal disease or dialysis 3. Known SCD (including sickle cell-beta thalassemia) 4. People who do not have SCT

Interventions

OTHER

Biologic Specimen Collection

Interested in This Trial?

Contact the trial locations directly using the information below to learn more about enrollment.

Expressing interest lets you review the study and consent before we connect you with the research site.

Conditions

Sickle Cell Trait

Locations

University of Alabama

Birmingham, Alabama 35294

United States

Loma Linda University Health Care

Loma Linda, California 92354

United States

Nemours Children's Hospital

Wilmington, Delaware 19803

United States

Indiana University

Indianapolis, Indiana 46202

United States

Functional Fluidics

Detroit, Michigan 48202

United States

University of North Carolina

Chapel Hill, North Carolina 27599

United States

Duke University

Durham, North Carolina 27710

United States

East Carolina University

Greenville, North Carolina 27834

United States

Nationwide Children's Hospital

Columbus, Ohio 43205

United States

UT Health Houston

Houston, Texas 77030

United States