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NCT06450353Recruiting

Prospective Evaluation of Disparities in Provision of Allogeneic Transplantation

M.D. Anderson Cancer Center

Start Date

5/31/2024

Completion Date

6/1/2029

Summary

To look at the effect of a recipient's ancestry and socio-economic status on their choice of bone marrow transplantation donor cells and their chance of receiving genetically similar (allogeneic) bone marrow cells versus cells that are not genetically similar (allograft).

Detailed Description

Primary Objectives To prospectively evaluate graft options and choice of donor by patient ancestry and SES for allograft candidates at MDACC. Secondary Objectives * To prospectively evaluate time to transplant for allograft candidates at MDACC. * To evaluate treatment-related mortality for allograft candidates at MDACC. * To assess overall survival for allograft candidates at MDACC. * To prospectively evaluate receipt of preferred unrelated donor for allograft recipients at MDACC. * To evaluate receipt of an optimal graft for allograft recipients at MDACC.

Eligibility Criteria

Age Range: 18 years to No maximum

Inclusion Criteria: 1. ≥ 18 years of age. 2. Candidate for allogeneic transplantation Exclusion Criteria: 1\) Allogeneic stem cell transplantation not medically indicated.

Interventions

BEHAVIORAL

Patient Ancestry Questionnaires

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Conditions

Allogeneic Transplantation

Locations

MD Anderson Cancer Center

Houston, Texas 77030

United States