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NCT07021547PHASE1RecruitingAccepts Healthy Volunteers

A Study of LY3867070 in Healthy Participants

Eli Lilly and Company

Start Date

5/27/2025

Completion Date

8/1/2026

Summary

The purpose of this study is to evaluate how well LY3867070 is tolerated and what side effects may occur in healthy participants. The study drug will be administered orally. Blood tests will be performed to investigate how the body processes the study drug and how the study drug affects the body.

Eligibility Criteria

Age Range: 18 years to 65 years

Inclusion Criteria: * Are overtly healthy as determined by medical evaluation * Part C of the study includes only Japanese and Chinese participants * Have a body weight greater than or equal to 45 kilogram (kg) and also body mass index 18 to 32 kilogram per square meter (kg/m²) inclusive Exclusion Criteria: * Have a history or presence of multiple or severe allergies, anaphylactic reaction to prescription or nonprescription drugs, or history of significant atopy * Have a significant history or current thyroid disease * Have a significant history of or current psychiatric disorders, rheumatologic, cardiovascular, respiratory, hepatic, renal, gastrointestinal, endocrine (such as Cushing syndrome and hyperaldosteronism), hematological, or neurological disorders * Are smokers (including electronic cigarettes) within 6 months prior to screening and unwilling to refrain from smoking for the duration of the study. * Unwilling to undergo skin biopsies (for Part B only) * Are unwilling to have body hair cut or shaved in cases where hair, in the investigator's opinion, could interfere with noninvasive skin patch

Interventions

DRUG

LY3867070

DRUG

Placebo

Interested in This Trial?

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Conditions

Healthy

Locations

Anaheim Clinical Trials, LLC

Anaheim, California 92801

United States

Fortrea Clinical Research Unit

Dallas, Texas 75247

United States