NCT07021547PHASE1RecruitingAccepts Healthy Volunteers
A Study of LY3867070 in Healthy Participants
Eli Lilly and Company
Start Date
5/27/2025
Completion Date
8/1/2026
Summary
The purpose of this study is to evaluate how well LY3867070 is tolerated and what side effects may occur in healthy participants. The study drug will be administered orally. Blood tests will be performed to investigate how the body processes the study drug and how the study drug affects the body.
Eligibility Criteria
Age Range: 18 years to 65 years
Inclusion Criteria:
* Are overtly healthy as determined by medical evaluation
* Part C of the study includes only Japanese and Chinese participants
* Have a body weight greater than or equal to 45 kilogram (kg) and also body mass index 18 to 32 kilogram per square meter (kg/m²) inclusive
Exclusion Criteria:
* Have a history or presence of multiple or severe allergies, anaphylactic reaction to prescription or nonprescription drugs, or history of significant atopy
* Have a significant history or current thyroid disease
* Have a significant history of or current psychiatric disorders, rheumatologic, cardiovascular, respiratory, hepatic, renal, gastrointestinal, endocrine (such as Cushing syndrome and hyperaldosteronism), hematological, or neurological disorders
* Are smokers (including electronic cigarettes) within 6 months prior to screening and unwilling to refrain from smoking for the duration of the study.
* Unwilling to undergo skin biopsies (for Part B only)
* Are unwilling to have body hair cut or shaved in cases where hair, in the investigator's opinion, could interfere with noninvasive skin patch
Interventions
DRUG
LY3867070
DRUG
Placebo
Conditions
Healthy
Locations
Anaheim Clinical Trials, LLC
Anaheim, California 92801
United States
Fortrea Clinical Research Unit
Dallas, Texas 75247
United States