The Cancer Stage Shifting Initiative: Registry and Biorepository to Research and Address Health Disparities in Cancer Care

Registry Inclusion Criteria: 1. Adults 35 years and older. 2. Participant provides written informed consent prior to initiation of any study procedures. 3. Participant understands the purpose and procedures of the study. 4. Participant agrees that demographic data, medical history, and social determinants of health on the enrollment questionnaires can be used for research purposes. 5. Participant agrees to the release and review of their electronic medical record. 6. Participant agrees to be followed for the duration outlined in this protocol. Biorepository 1. Participant is able, in the investigator's professional opinion, to provide up to 100 mLs of whole blood at the Screening Visit and at the Interim Visits. 2. Participant is a healthy, nonpregnant adult. 3. Participant weighs at least 110 pounds. 4. Participant has negative viral test results. Exclusion Criteria: Registry 1. Any medical or mental condition that would interfere with the subjects' ability to willingly give written informed consent. 2. Participants who are unable to understand the study protocol or unable to give informed consent. 3. Participants under the age of 35 at the time of enrollment. Biorepository 1. Women of childbearing age that think they may be pregnant or are planning to get pregnant within the study timeframe. 2. Participants who weigh under 110 pounds. 3. Participants who, in the opinion of the investigator, are unable to provide biospecimen samples.