Phase 2/3 Efficacy and Safety of PP405 in Adult Males
Start Date
9/21/2026
Completion Date
6/1/2028
Summary
The study is designed to validate efficacy and long term safety of PP405.
Detailed Description
Participants will initially be randomized 1:1 to PP405 or vehicle and complete a 24 week double blinded treatment period. At Week 24, the PP405 group will continue PP405 treatment, and the vehicle group will be re-randomized 1:1 to PP405 or vehicle for the double-blind long term safety extension period through study week 52.
Eligibility Criteria
Age Range: 18 years to 55 years
Interventions
PP405 0.05% Topical Gel
Vehicle Topical Gel
Conditions
Locations
AllerVie Clinical Research
Birmingham, Alabama 35209
United States
Johnson Dermatology
Fort Smith, Arkansas 72916
United States
Burke Pharmaceutical Research
Hot Springs, Arkansas 71913
United States
Ablon Skin Institute and Research Center
Manhattan Beach, California 90266
United States
Clinical Trials Research Institute
Thousand Oaks, California 91230
United States
Skin Research Institute, LLC
Coral Gables, Florida 33146
United States
MOORE Clinical Research, Inc.
Tampa, Florida 33607
United States
DelRicht Research (Experience Dermatology)
Atlanta, Georgia 30329
United States
Dawes Fretzin Clinical Research Group, LLC
Indianapolis, Indiana 46256
United States
Indiana Clinical Trials Center
Plainfield, Indiana 46168
United States
DelRicht Research @LA Dermatology Associates
Baton Rouge, Louisiana 70809
United States
Minnesota Clinical Study Center
New Brighton, Minnesota 55112
United States
DelRicht Research (Town Center Dermatology)
Wildwood, Missouri 63040
United States
Vitality Clinical Trials LLC
Woodbury, New York 11797
United States
Optima Research Boardman
Boardman, Ohio 441512
United States
DelRicht Research @Mt Pleasant Dermatology
Mt. Pleasant, South Carolina 29464
United States
AMR Clinical - Myrtle Beach
Myrtle Beach, South Carolina 29588
United States
Dermatology and Laser Surgery Center
Houston, Texas 77002
United States
Texas Dermatology & Laser Specialists
San Antonio, Texas 78218
United States
Jordan Valley Dermatology Center
South Jordan, Utah 84095
United States
Eurofins CRL Cosmetic LLC
Forest, Virginia 24551
United States
Innovaderm Research Inc
Montreal, Quebec H2X2V1
Canada