Major Depressive Disorder Clinical Trials
Major Depressive Disorder clinical trials evaluate new treatments, behavioral therapies, and medications for major Depressive Disorder. Corterve compiles actively recruiting Major Depressive Disorder studies from the ClinicalTrials.gov registry so you can search by location and eligibility criteria. Participation is always voluntary and confidential. This information is educational and not medical advice — talk with a licensed clinician about whether a study is right for you.
Recruiting Major Depressive Disorder studies
- Neuropharmacologic Imaging and Biomarker Assessments of Response to Acute and Repeated-Dosed Ketamine Infusions in Major Depressive DisorderNCT03065335PHASE1National Institute of Mental Health (NIMH)Healthy VolunteerBethesda, Maryland
- A Study to Evaluate the Effectiveness of DT-101 in Patients With DepressionNCT07300969PHASE2Draig Therapeutics LtdMajor Depressive Disorder (MDD)Bentonville, Arkansas
- Pilot Study: Establishing Glutamatergic Changes in Rapid Antidepressant Effects of KetamineNCT06788249EARLY_PHASE1University of PennsylvaniaMajor Depressive Disorder (MDD)Philadelphia, Pennsylvania
- Stress Management and Meditative Movements for Asian Americans With Depression and Physical SymptomsNCT07610928NAMassachusetts General HospitalDepression / Major Depressive DisorderBoston, Massachusetts
- A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)NCT07065240PHASE2Seaport TherapeuticsMajor Depressive Disorder (MDD)Chino, California
- Closed-Loop Transcranial Alternating Current Stimulation for the Treatment of Major Depressive DisorderNCT07282678NAPulvinar Neuro, LLCDepression - Major Depressive DisorderDurham, North Carolina
- IMST for Dementia Risk ReductionNCT07349706NAFlorida State UniversitySystolic Blood PressureTallahassee, Florida
- ACP-211 Monotherapy for Major Depressive Disorder With Inadequate Antidepressant ResponseNCT07284667PHASE2ACADIA Pharmaceuticals Inc.Major Depressive Disorder (MDD)Birmingham, Alabama
- A Phase 3 Trial of DT120 for Major Depressive Disorder (Ascend)NCT07592689PHASE3Definium Therapeutics US, Inc.Major Depressive DisorderLittle Rock, Arkansas
- A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive DisorderNCT06793397PHASE3Cybin IRL LimitedMajor Depressive Disorder (MDD)Birmingham, Alabama
- Natural History of Depression, Bipolar Disorder and Suicide RiskNCT06462196National Institute of Mental Health (NIMH)Behavioral SymptomsBethesda, Maryland
- Development of Attentional Biases for Affective Cues in Infants of Mothers With DepressionNCT06835855NABinghamton UniversityDepression - Major Depressive DisorderBinghamton, New York
Major Depressive Disorder trials by state
Major Depressive Disorder trials by metro
Frequently asked questions
- How do I find recruiting Major Depressive Disorder clinical trials?
- Browse the actively recruiting Major Depressive Disorder studies listed on this page, or take an assessment to see trials you may qualify for based on your profile.
- Are Major Depressive Disorder clinical trials free to join?
- Costs, travel support, and any payment for taking part vary by study. Ask the study team what is covered before you decide to join.
- Who can take part in a Major Depressive Disorder clinical trial?
- Each study has its own eligibility criteria (for example age, disease stage, and prior treatments). This page is general information and not medical advice; discuss any specific trial with your healthcare provider to confirm whether it is appropriate for you.